Rupa Health Alternatives: Fullscript Labs vs Evexia vs Vibrant Wellness (2026)

Three common Rupa Health alternatives for practitioners are Fullscript Labs, Evexia Diagnostics and Vibrant Wellness. Fullscript is Rupa’s direct successor and imports Rupa data for free. Evexia covers Labcorp plus 30+ specialty labs and, on its paid tier, lets you set your own patient prices, outside New York, New Jersey and Rhode Island. Vibrant is a single specialty lab that licensed providers order from directly.

Rupa became view-only on October 30, 2026 and its login closes January 20, 2027, so every Rupa practice needs a new place to order. If you haven’t handled your open orders and data yet, start with our guide to Rupa Health closing. This page compares where to order next. The three platforms are listed alphabetically, and each fits a different kind of practice. Every fact below comes from the company’s own pages, linked in the sources.

Quick Comparison

Fullscript Labs: For Practices That Want the Easiest Move

Fullscript bought Rupa and is where Rupa accounts are moving. Its move page says order history, patients, panels and bundles transfer automatically, with “the same lowest provider pricing you already know.”

Who can order. Fullscript says your lab access depends on each lab company’s requirements, including your state, license and NPI. A practice can assign a signing practitioner from its own team. Practitioners without one can opt into the authorization network, recommend tests from a curated list, and have a signing clinician review each order for $9.50 per test or panel. The network isn’t available to providers based outside the US.

Test menu. Fullscript Labs lists more than 2,500 blood labs and specialty tests under one login. Fullscript hasn’t published a test-by-test match against Rupa’s catalog.

Blood draws. Fullscript offers Quest draws and Labcorp testing through Access Labs, which gives patients “access to Labcorp’s national patient service center network for specimen collection.”

How patients pay. Under Fullscript’s billing options, the patient pays through Fullscript by default. The practitioner can instead pay upfront and bill the patient separately, or add an itemized custom fee at checkout. Fullscript applies a 5% processing fee to custom fees and adds them to the practitioner’s regular payout, every 30 days by default. Practices can also run a Fullscript storefront with their own logo, where patients see one bundled price at checkout.

Fees. Practitioner accounts are free. Patients pay a 3% service fee on specialty tests, which doesn’t apply to blood labs or to orders in New York, New Jersey or Rhode Island. Quest draws carry a flat $10 fee.

Best for: a Rupa practice that wants its history, panels and billing options intact, needs both blood work and specialty kits, and may want supplement dispensing in the same account.

Evexia Diagnostics: For Practitioners Who Want Labcorp, Specialty Labs and Their Own Pricing

Evexia is an ordering platform that gives one account access to “30+ CLIA-certified laboratories” and thousands of tests. Its laboratory partners page names 42 labs, including Labcorp, Genova Diagnostics, Precision Analytical (DUTCH), Doctors Data, Mosaic Diagnostics, Boston Heart, ZRT and Access Medical Labs. Quest is not on the list.

Who can order. Licensed clinicians order under their own license. Evexia’s clinician agreement says non-licensed clinicians may use the Evexia Internal Physician Network, where an Evexia physician signs the order. The agreement lists a $5 physician oversight fee per Client Bill order and $6 per EvexiaDirect or promo page order. Healthie’s Evexia integration FAQ cites a $15 requisition and doctor fee per order for non-licensed providers, so confirm the current figure when you sign up.

How patients pay. Under Client Bill, the agreement says “You pay Evexia and then set your own patient pricing.” It lists Client Bill among the features of EvexiaComplete, which costs $50 a year, so confirm with Evexia which tier you need for your own pricing. Under EvexiaDirect, the patient pays Evexia through a portal before testing proceeds, with a 3% processing fee.

Draw options. Blood work can be drawn at Labcorp patient service centers for a $10 collection fee per specimen, or by Evexia’s network of “over 6,000 carefully selected mobile phlebotomists” at the office or the patient’s home. Evexia’s mobile phlebotomy page doesn’t list a fee for that service.

Fees. Test prices are visible only after you create a free account. (Karpa doesn’t publish its labs-only pricing either; it shares it on a call.) Published fees include a $50 annual participation fee for EvexiaComplete and a $75 fee for each chargeback or failed ACH draft.

State limits. The agreement states that Evexia “does not do business in NY, NJ, and RI.”

Best for: a practitioner outside New York, New Jersey and Rhode Island who orders Labcorp panels alongside specialty kits, wants to set patient prices themselves, and may need a signing physician.

Vibrant Wellness: For Licensed Providers Who Order Vibrant’s Own Panels

Vibrant Wellness is a lab, not an ordering platform. Its tests run “in a CLIA-certified and CAP-accredited lab in Santa Clara, California,” and its menu is built around its own Zoomer panels (Gut, Hormone, Cardio, Toxin, Cellular, Food, Foundation, Immune, Neural and Nutrient) plus infection and genetic tests. If your Rupa orders were mostly DUTCH, Genova or Quest, Vibrant replaces only the part of your menu that Vibrant itself runs.

Who can order. Vibrant’s testing policy says it “allows providers to order tests for their patients,” and its terms of use require the provider to confirm they are “authorized by State law to order all non-waived tests” for each patient. Vibrant says it “does not provide physician services.” We found no signing-physician network on Vibrant’s public pages, so a non-licensed practitioner would need their own ordering clinician.

How patients pay. Testing is cash pay only and must be paid before it is completed. Either the patient or the provider pays by card at ordering. Patients can use a debit or credit card, HSA or FSA, or pay later with Afterpay or Klarna. Vibrant no longer accepts commercial insurance or Medicare and doesn’t provide superbills. Vibrant prices tests through a test price calculator on its site and doesn’t publish whether or how practitioners mark tests up.

Draw options. Vibrant’s provider page lists “over 2000 draw sites and mobile phlebotomists,” kits that ship within 24 hours, and the option to build your own kit. Collection types include blood draw, urine, stool, saliva and dried blood spot.

Fees. Account fees aren’t published. The terms list a $25 cancellation fee if an order was paid and the kit shipped.

State limits. Vibrant doesn’t publish a general list of state restrictions. In August 2026 it announced that a New York version of Gut Zoomer is “available immediately for patients with a New York shipping address.” It didn’t say which other tests are available in New York.

Best for: a licensed provider whose testing centers on Vibrant’s Zoomer panels and who is comfortable with a direct lab account instead of a multi-lab platform.

Are There Other Ways to Order?

Yes. These three aren’t the only options. Some practices open accounts directly with the specialty labs they use most, such as DUTCH or Genova, instead of going through a platform. Others order from inside their practice software. Practice Better integrates with Evexia for lab ordering, and Healthie’s Evexia integration brings Evexia results into the patient chart. Check which labs your practice software connects to before you pick a platform.

How Do the Three Compare for Non-Licensed Practitioners?

This is the question most former Rupa Physician Services users need answered first.

• Fullscript keeps the closest equivalent. You recommend tests from a curated list, a signing clinician reviews and appears on the requisition, and the patient pays Fullscript. Former Physician Services users see the opt-in when they move.
• Evexia has its own physician network that signs orders, with a per-order oversight fee. It isn’t available in New York, New Jersey or Rhode Island.
• Vibrant publishes no signing-physician service. The ordering provider must be authorized under state law.

In all three, the checkout runs on the platform or the lab, and the platform processes the patient’s payment or bills you. You earn through a custom fee or payout (Fullscript) or by setting your own patient price after paying Evexia (Client Bill). Fullscript storefronts can carry your logo. Our guide to who can order lab tests covers the state rules behind this.

What About Businesses That Sell Standard Blood Panels Under Their Own Brand?

Some Rupa users weren’t practitioners at all. They were gyms, coaches or wellness brands that used Rupa to offer testing to customers. If that’s you, and the tests you sell are standard blood panels rather than specialty kits, a provider-ordered white label model is a fourth option.

On Karpa, a licensed provider in Karpa’s independent network orders every test, so the business needs no medical license. Customers buy from a storefront under your brand, at a price you set. The main difference from the platforms above is where the money lands: payments settle to your own Stripe account rather than to the platform. Karpa doesn’t publish its labs-only storefront pricing; it shares it on a call. Labcorp runs the tests, customers walk in or book a draw at a Labcorp patient service center, and each order carries a $6 collection fee. Coverage is 47 states plus Washington DC. Branded at-home kits, including Tasso devices, launch December 1, 2026.

When Karpa is not the right fit:

• You need specialty kits. Karpa does not offer specialty kit tests from labs like DUTCH, Genova or Vibrant. For GI-MAP, hormone metabolite or Zoomer panels, use Fullscript, Evexia or Vibrant.
• You’re a licensed practitioner choosing tests patient by patient. A practitioner ordering platform fits that workflow better than a storefront.
• You need results reviewed by a provider by default. Karpa results go to the customer’s branded portal, and a provider reviews them only if the customer books a TRT or HRT consult.
• Your customers are in Hawaii, Maine or North Dakota, where Labcorp has no patient service center.

For the full field of white label options, see the best white label lab testing companies and Karpa vs Rupa Health. To set your retail prices, see how much to charge for lab tests.

How to Choose

Match the platform to how your practice orders:

• You want the least disruption and need blood work plus specialty kits: Fullscript Labs.
• You want Labcorp and 30+ specialty labs with your own patient pricing, outside NY, NJ and RI: Evexia Diagnostics.
• You mostly order Vibrant’s Zoomer panels and hold a license to order: Vibrant Wellness, directly.
• You’re a non-licensed business selling standard Labcorp panels under your own brand: a provider-ordered white label model such as Karpa.

Many practices will use more than one. Fullscript practitioner accounts are free, moving your Rupa data there keeps patient history in one place, and you can still open an Evexia or Vibrant account for the tests you order most. Whatever you choose, finish moving or downloading your Rupa data before the login closes on January 20, 2027.