MOTS-c Mitochondrial Peptide Screening Form Template

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondria-derived peptide that regulates metabolic homeostasis, insulin sensitivity, and exercise endurance. It is prescribed off-label through compounding pharmacies for metabolic dysfunction, weight management, and physical performance optimization. This screening form documents metabolic symptoms and screens for conditions including insulin resistance, malignancy, and mitochondrial disorders before initiating MOTS-c therapy.

4 sections
17 fields
HIPAA-ready
3 citations

Free Template

MOTS-c Peptide Screening Form

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Your Practice Name

MOTS-c Peptide Screening Form

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1

General Patient Information

Please provide your personal information.

First Name

Jane

Last Name

Smith

Date of Birth

Can you confirm you are 18 years or older?

Height

e.g. 5'8"

Weight

e.g. 170 lbs

2

Medical History

Please answer all questions as accurately as possible. Your provider will review this information.

Are you actively taking any medications? If so, please list them.

List all current medications, dosages, and frequencies

Do you have any medication allergies? If so, please list them.

List all known drug allergies and reactions

Are you currently being treated or have you been treated for any medical conditions? If so, please list them.

List all current and past medical conditions

Have you had any past surgeries? If so, please list them.

List all surgeries and approximate dates

What is/was your sex assigned at birth?

Male

Emergency contact name and phone number

Name — (555) 000-0000

Mailing address

123 Main St, City, State, ZIP

Any other questions or concerns?

Optional — share anything else you'd like your provider to know

3

Symptoms

Select all symptoms that currently apply to you.

Which of the following symptoms are you experiencing?
4

Medical Conditions

Select all conditions that currently apply to you.

Do any of the following apply to you?

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Compliance & Regulatory Notes

Review these notes before deploying this form in your practice.

MOTS-c is not FDA-approved and is prescribed off-label. Documented informed consent is required. See FSMB: https://www.fsmb.org

MOTS-c improves insulin sensitivity, which may affect glucose management in diabetic patients. Monitor blood glucose closely in patients on insulin or hypoglycemic agents.

MOTS-c must be dispensed by a licensed compounding pharmacy. See FDA: https://www.fda.gov/drugs/human-drug-compounding

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Sources & References

  1. FDA Human Drug Compounding Guidance
  2. FSMB Off-Label Prescribing Guidelines
  3. NIH - MOTS-c Mitochondrial Peptide Research

Frequently Asked Questions

What makes MOTS-c different from other metabolic peptides?

MOTS-c is unique as a mitochondria-derived peptide (mitokine) that directly regulates cellular energy metabolism and insulin signaling. Unlike growth hormone secretagogues, it does not stimulate GH and has a distinct metabolic mechanism.

Can MOTS-c be used for weight loss?

MOTS-c is studied for its role in metabolic regulation and may support weight management as part of a comprehensive metabolic health protocol. It is not a standalone weight loss treatment and works best alongside lifestyle interventions.